It is not possible to be original by trying to be original - those who attempt this in the arts will be merely avant-garde. Originality is the product of an impulse to intense and overwhelming that it bursts the conventions and produces something new - again more by accident than design.
I picture the vast realm of the sciences as an immense landscape scattered with patches of dark and light. The goal towards which we must work is either to extend the boundaries of the patches of light, or to increase their number. One of these tasks falls to the creative genius; the other requires a sort of sagacity combined with perfectionism.